Fig. 5From: Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytesDNA methylation is increased in the promoters of germline master regulator genes. The average values for the methylated DNA-to-input ratios were calculated and plotted. The DNA methylation levels of promoter LINE-1 (L1) retroelements were used as positive controls. A nonparametric Mann–Whitney test was used to assess statistical significance, and the exact p-values are indicated at the tops of the columnsBack to article page