Skip to main content
Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Histone deacetylase inhibition leads to regulatory histone mark alterations and impairs meiosis in oocytes

Fig. 4

Gestational exposure to PB alters developmental genes, transcription factors and genes encoding Zn-finger proteins. Gene expression analysis was performed by RNA transcriptomic analysis using 3 biological replicates from control and PB-exposed E15.5 ovaries. Gene Ontology function analysis of the downregulated (A) and upregulated genes B was performed. C Analysis using the CHEA2016 dataset from Enrichr showed that many DEGs are regulated by gonad differentiation-specific genes (DMRT1, SOX9). D Heatmap illustrating the subset of DEGs encoding the cell cycle, DNA repair, and transcription factors

Back to article page

Epigenetics & Chromatin

ISSN: 1756-8935