Fig. 3

Dim2 is the main DNA methyltransferase in V. dahliae. a Whole-chromosome plot displaying the fraction of methylated cytosines for non-overlapping 10-kb windows for wild-type, and DNMT and Hp1 deletion mutants with chromosome 5 as an example. Grey boxes, displayed below the DNA methylation tracks, indicate the hypomethylated windows compared to the wild-type strain in CG and CHG context from Table 1. Previously defined adaptive genomic regions [23] are highlighted in yellow. b Overlap of hypomethylated windows in mutant strains showing severe loss of methylation. c Expression (TPM values) of DNA methyltransferase genes Dim2, Dnmt5 and Rid, as well as Hp1 and Dim5 of V. dahliae strain JR2 cultured in Czapec–Dox medium (CZA), half-strength Murashige–Skoog medium (MS) and potato dextrose broth (PDB), and during Arabidopsis infection at 21 days post inoculation (Arab), in triplicates