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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Early-life undernutrition induces enhancer RNA remodeling in mice liver

Fig. 2

Impact of maternal PRD on nascent transcripts. a, b The dot plot graph shows all differentially expressed nascent RNA based on the fold change and p value. Blue dots represent down-regulated transcription and red dots represent up-regulated transcription. c, d Heatmap of log2-transformed fold changes of RNA polymerases ± 5 kb from TSSs with 200 bp bin size for all nascent active genes from maternal PRD and NCD livers at the ages of 4 weeks and 7 weeks, respectively. e Differentially expressed genes between the offspring of the dams fed the PRD and NCD at the age of 4 weeks and 7 weeks in GRO-seq were analyzed by Kyoto Encyclopedia of Genes and Genomes (KEGG). Fold change > 1.5, p < 0.05

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