Histone crotonylation-centric gene regulation

Table 1 The regulatory factors for histone crotonylation

Factor	Regulatory pattern	Crotonylation site	References
P300	Writer	H3K18	[15]
MOF		H3K4, H3K9, H3K18, H3K23, H4K8, and H4K12	[17]
GCN5		H3K9, H3K14, H3K18, H3K23, and H3K27	[18]
Esa1		H4K5, H4K8, H4K12, and H4K16	[18]
SIRT 1, 2, 3	Eraser	H3K4	[19]
HDAC1, 2, 3	Eraser	H3K4, H3K9, H3K23, H4K8, H4K12 (HDAC1), and H3K23 (HDAC2, 3)	[20]
Taf14	Reader	H3K9	[26]
YEATS2		H3K27	[27]
AF9		H3K9, H3K18 and H3K27	[28]
MOZ and DPF2		H3K14	[29]
NEAT1	Regulator with unknown mechanism	H3K27	[8]
CDYL		H2BK12, H3K9, H3K27, and H4K8	[10]
ACSS2		H3K4 and H3K18	[12, 15]
RNF8		/	[33]

ISSN: 1756-8935