Fig. 1
From: Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk
Light microscopy and flow cytometric characterisation of cultured cells at day 22. Cultured cells of adult origin with media containing 0 nM calcitriol (left), 0.1 nM calcitriol (centre) and 50 nM calcitriol (right). There were marked morphologic and immunophenotypic changes, with overall decrease in cell number, fewer fusiform-shaped cells, greater CD14+ proportion and decreases in HLA-DR and CD16 expression (not shown) at higher calcitriol concentrations