Fig. 1
From: Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation
BET inhibition suppresses melanin synthesis. Melb-a cells were differentiated for the indicated number of days in the presence or absence of the BET bromodomain inhibitor (+)JQ1 (500 nM). Cells were pelleted and a photographed or b subjected to a melanin assay (UN untreated, VC vehicle treated). The results are the average three independent experiments. Standard error bars are shown. Statistically significant differences between VC and (+)JQ1 are shown (*p < 0.05, **p < 0.01, ***p < 0.001)