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Table 2 Description of HM450K DNAme datasets used to develop and test PlaNET

From: Accurate ethnicity prediction from placental DNA methylation data

Cohort (n)

GEO accession

Dataset summary

Location

Self-reported ethnicity

Non-HM450K genetic data (n)

AFR (n = 57)

ASI (n = 53)

CAU (n = 389)

C1 (72)

GSE70453

36 controls, 36 gestational diabetes mellitus

Boston, MA, USA

13

13

46

N/A

C2 (24)

GSE73375

13 controls, 11 preeclampsia (PE)

Chapel Hill, NC, USA

13

1

10

N/A

C3 (289)

GSE75248

289 samples from infants with variable newborn neurobehavior

RI, USA; MA, USA

23

9

257

N/A

C4 (44)

GSE100197

17 controls, 27 PE

Toronto, CAN

7

12

25

50 AIMs (41)

C5 (70)

GSE100197, GSE108567, GSE74738, unpublished

35 controls, 35 fetal growth restriction, PE, and/or preterm birth

Vancouver, CAN

1

18

51

50 AIMs (67); Omni2.5 (27)

  1. AFR African, ASI Asian, CAU Caucasian