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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

Fig. 6

ZFP57 maintains DNA methylation at both imprinted and non-imprinted regions during preimplantation development. DNA methylation levels of non-DMRs, oocyte and sperm-specific germline DMRs bound by ZFP57 (darker colored) versus those not bound by ZFP57 (light colored) during preimplantation development and in E6.5 epiblast and extraembryonic ectoderm [30,31,32]. Known ICRs are shown as hatched boxes for comparison. ICM, inner cell mass; TE, trophectoderm; ExE, extraembryonic ectoderm; ns, not significant, *P < 0.05, **P < 0.01, ***P < 0.001; Mann–Whitney U test

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