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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling

Fig. 3

SEACR thresholding provides an improved specificity/sensitivity trade-off. a Precision–recall curves derived from a comparison of peaks called from subsampled H3K4me2 CUT&RUN to ENCODE peaks called from H3K4me2 ChIP-seq data. Colors denote peak calling method, size of points denotes read subsampling level, and dotted black line denotes 85% precision in peak calling. b F1 score for each point on the plots in A

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