Fig. 6
From: H3K4me2 functions as a repressive epigenetic mark in plants
H3K4me2 distribution patterns and functions vary in yeast, animals, and plants. a Heatmaps presenting the genome-wide H3K4me2 distributions in various species. The plots were generated from 3 kb upstream of the TSS to 3 kb downstream of the TTS. From left to right: C. elegans, D. melanogaster, mouse embryonic stem cells (mESCs), human colon cancer cell line (HCT116 cells), S. cerevisiae, Arabidopsis, and rice. b Average density plots presenting the H3K4me2 distributions along differentially expressed genes in various species. The plots were generated from 3 kb upstream of the TSS to 3 kb downstream of the TTS. (Non: 0 < FPKM < 1; Low: 1 < FPKM < 2; Middle: 2 < FPKM < 10; and High: FPKM > 10). c Scatter plots presenting the relationship between the H3K4me2 level and the gene transcription level. The H3K4me2 levels were calculated as follows: ChIP-seq normalized read density—input normalized read density for expressed genes (FPKM > 1). Spearman’s rank correlation coefficient indicates the correlation between the methylation level and the gene expression level. The p value was determined based on Spearman’s rank correlation test