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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors

Fig. 7

Absence of functional Sp1 results in highly disordered differentiation trajectories. a Pseudotime trajectory plots of WT and Sp1ΔDBD/ΔDBD Kit + sorted cells from day 2 of blast culture. Each dot represents the transcriptome of a single cell, colour coded according to the assigned cellular identity as shown to the right of the panels. b Expression patterns of selected TFs projected on the trajectory plots for WT and Sp1ΔDBD/ΔDBD from day 2 of blast culture

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