Fig. 5From: Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sitesDNA methylation changes are located in small regions which are enriched for changes in DNAseI hypersensitive sites and TF-binding sites. a Histogram depicting the number of DMRs harboring a specific amount of CpGs. b Histogram depicting the number of DMRs having similar length of region in base pairs. c Enrichment analysis for DNAseI hypersensitive sites for gain (red) and loss (blue) of DNA methylation compared to genome-wide DNAseI hypersensitive sites. d Motif analysis with HOMER for transcription factor binding sites on differential DMCs for gain (left) and loss (right) of DNA methylation. e Enrichment analysis of transcription factor binding of C/EBP and PU.1 at their motifs for gain-DMCs during monocyte-to-macrophage differentiationBack to article page