Fig. 1From: Dam mutants provide improved sensitivity and spatial resolution for profiling transcription factor bindingqPCR for Dam-Tcf7l2 methylation at control sites. Fraction of sequences methylated is estimated by qPCR at four positive Tcf7l2 ChIP-seq (red) regions compared to four DNase hypersensitive regions (blue) distal to any Tcf binding following expression of Dam or Dam-Tcf7l2 constructs for 8 (wild-type) or 24 h (mutants). Mean ± SDBack to article page