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Fig. 8 | Epigenetics & Chromatin

Fig. 8

From: Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Fig. 8

Motif and function analysis of Pax6 binding sites at open and closed chromatins. a Top enriched motifs at Pax6 binding sites at open and closed chromatins in lens and E12.5 forebrain. b Pie charts show the genomic distributions of the Pax6 peaks at open and closed chromatin in lens and E12.5 forebrain. c Dot plot shows enriched GO terms for Pax6 peaks at open and closed chromatins in lens and E12.5 forebrain. The dot color represents –log10(FDR), and the dot size represents number of regions in the GO terms. d Raincloud plots show the expression of genes with Pax6 peaks at open and closed chromatin regions in P1 epithelium and fibers as well as E12.5 forebrain. The * indicates p < 0.05 by Mann–Whitney U test

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Epigenetics & Chromatin

ISSN: 1756-8935