Fig. 1
From: Histone H3 lysine K4 methylation and its role in learning and memory
Cognitive diseases associated with dysregulation of H3K4 methylation. Associated diseases fall under three different DSM-5 groupings: Neurodevelopmental disorders, schizophrenia spectrum and other psychotic disorders, and substance-related and addictive disorders. Neurodevelopmental disorders encompass both ID and ASD. Beneath each DSM-5 disorder is an icon that either symbolizes the disorder or depicts a key clinical feature of it (Far left: A collection of puzzle pieces, representing the complexity of genetic and non-genetic etiologies of ID. Middle left: A blue puzzle piece, one of the symbols of ASD used by advocacy organizations. Middle right: A representation of visual and auditory hallucinations experienced by patients with schizophrenia. Far right: A prescription bottle of hydrocodone, representing one of the compounds used by patients with this disorder)