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Table 2 Comparison of binding site and epigenetic mark occupancy in A/B compartments between two cell types

From: Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

(A) CTCF; HMEC–HUVEC AA AB BA BB Total R p value
 HMEC only CTCF BSs 7241 1655 947 4775 14,618 2.34 10−168
 HUVEC only CTCF BSs 4516 264 1180 1524 7484   
 Common CTCF BSs 24,986 2587 4647 9750 41,970   
(B) H3K9ac; GM12878-NHEK AA AB BA BB Total R p value
 GM12878 only H3K9ac peaks 14,695 3111 596 1708 20,110 4.54 < 10−300
 NHEK only H3K9ac peaks 19,997 1401 5949 4154 31,501   
 Common H3K9ac peaks 21,594 2036 1078 2911 27,619   
(C) H3K27me3; MCF7-GM12878 AA AB BA BB Total R p value
 MCF7 only H3K27me3 peaks 5213 1751 3637 9712 20,313 0.54 10−122
 GM12878 only H3K27me3 peaks 7176 1765 1145 3608 13,694   
 Common H3K27me3 peaks 318 95 118 317 848   
  1. Preference to cell-type specific A/B compartment is emphasized in italics
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Epigenetics & Chromatin

ISSN: 1756-8935