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Fig. 8 | Epigenetics & Chromatin

Fig. 8

From: Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten

Fig. 8

Comparison of methylation correlation between HiSeq 2500 and HiSeq X Ten. a Correlation plots of methylation levels obtained from a cell line, a clinical sample and a FFPET sample sequenced on the Hiseq 2500 versus HiSeq X Ten (Pearson r > 0.94). b Correlation of methylation values obtained from HiSeq 2500 and HiSeq X Ten for a cell line, clinical sample and a FFPET sample after grouping them into four bins of methylation percentages. c Average kappa values for six sample pairs, including two cell lines, two clinical samples and two FFPE samples compared between the HiSeq 2500 and HiSeq X Ten platform. d Bar plot showing the distribution of percentage of discordant sites across the genome for a cell line, clinical sample and a FFPET sample

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Epigenetics & Chromatin

ISSN: 1756-8935