Table 2 Motif overrepresentation analysis
Gene | Motif ID | Motif source | Species | Poisson p value | Enrichment score ratio (max/outlier) | Judgment |
|---|---|---|---|---|---|---|
RUNX3 | RUNX3 | jolma2013 | Hsapiens | 2.07E−33 | 15.48 | DNA demethylating |
GATA2 | MA0036.1 | JASPAR_CORE | Hsapiens | 1.16E−29 | 4.29 | DNA demethylating |
CEBPB | MA0466.1 | JASPAR_2014 | Hsapiens | 7.87E−250 | 13.80 | DNA demethylating |
MAFB | Mafb | jolma2013 | Mmusculus | 6.41E−52 | 11.99 | DNA demethylating |
NR4A2 | MA0160.1 | JASPAR_CORE | Mmusculus | 5.89E−72 | 9.76 | DNA demethylating |
MYOD1 | MA0499.1 | JASPAR_2014 | Mmusculus | < 1E−320 | 23.64 | DNA demethylating |
CEBPA | MA0102.2 | JASPAR_CORE | Vertebrata | 1.15E−89 | 7.96 | DNA demethylating |
TBX5 | TBX5 | jolma2013 | Hsapiens | 4.11E−174 | 13.14 | DNA demethylating |
NANOG | NA | SwissRegulon | NA | 0.90 | NA | Non-DNA demethylating |
HNF1A | HNF1A | jolma2013 | Hsapiens | 0.12 | NA | Non-DNA demethylating |
PAX4 | MA0068.1 | JASPAR_CORE | Mmusculus | 1.00 | NA | Non-DNA demethylating |
Nkx2-5 | UP00249 | UniPROBE | Mmusculus | 1.00 | NA | Non-DNA demethylating |
SOX2 | MA0143.1 | JASPAR_CORE | Mmusculus | 0.38 | NA | Non-DNA demethylating |
POU5F1 | MA0142.1 | JASPAR_CORE | Mmusculus | 0.50 | NA | Non-DNA demethylating |
HNF4A | HNF4A | jolma2013 | Hsapiens | 0.06 | NA | Non-DNA demethylating |