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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads

Fig. 5

Transcriptomic effects in ovaries treated with 75 µM of 5-aza-dC during gonadal development (10–30 dpf). a Clustering of fish based on their ovarian transcriptomic profiles at 90 dpf as assessed by principal component analysis (PCA). Per cent values refer to variance (total variance explained ~ 75%). b Description of the number of differentially expressed genes (white numbers) according to different fold change values with a P < 0.01. c Gene expression at 90 dpf in zebrafish ovaries of some reproduction-related genes present in the microarray. Full gene names are listed in Additional file 5: Table S2

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