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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits

Fig. 2

RNA-seq in BRG1, BRM and combined knockdown. a Western blot of HepG2 cells treated with shRNA targeting BRG1, BRM or both combined. b Log2 normalized read counts of RNA-seq data HepG2 treated with BRG1, BRM or both combined shRNA. c Morphology changes of shRNA conditions. d GSEA analysis of expression changes following shRNA targeting BRG1 and BRM. f Fold changes of genes significantly differentially expressed and bound by BRG1 and BRM. g Effect on genes in f following treatment with the individual and double knockdown shRNA

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