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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx

Fig. 5

CENP-B and Daxx knockout increases chromosomal instability (CIN). Analysis of chromosome number in HEp2 and MCF7 cells; thick vertical line marks median of modal chromosome number, whiskers show min and max. Higher range of deviation from mean of modal chromosomal number was observed in CENP-B and Daxx knockout cell lines compared to control cells, that is indication of CIN. ***P < 0.001; ****P < 0.0001

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