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Table 2 TFs regulating more macrophage-specific than non-macrophage-specific enhancers

From: Genome-wide profiling of transcribed enhancers during macrophage activation

TF

Mean TPM in macrophages

% Macrophage-specific enhancers

% Non-macrophage-specific enhancers

Ratio

Stat1

284.6

15.8

8.5

1.9

Rela

130.7

26.6

14.5

1.8

Atf4

329.4

25.5

14.3

1.8

Irf1

508.7

21.7

12.2

1.8

Junb

176.3

11.2

7.4

1.5

Spi1

599.9

54.1

38

1.4

Cebpb

647.9

48

34.8

1.4

  1. Columns show TF name, average expression in macrophage samples (in TPM, see “Methods”), percentage of enhancers overlapping corresponding binding sites, and a macrophage-specific/non-macrophage-specific percentage ratio. TFBSs are statistically significantly enriched in both enhancer sets
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Epigenetics & Chromatin

ISSN: 1756-8935