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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics

Fig. 6

K99R alteration makes the H2A1H-containing nucleosomes more stable. a, b Comparative analysis to determine the percentage of recovery after photo bleaching, for 1 h amongst various H2A1H single, double mutants and H2A2A3 with H2A1H. Error bar represents SEM of ten independent experiments. c Comparative determination of the hydrogen bonds formed by three differential residues (16th, 51st and 99th) with their neighboring residues in H2A1H and H2A2A3 during MDS of nucleosomes. Error bar represents SEM of three independent experiments. d, e Ligplot depicting the hydrogen and hydrophobic interactions of the 99th residue of (d) H2A1H and e H2AA3 with the neighboring residues

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