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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

Fig. 3

DNA methylation variability was lower in Nicoyans. a Scatter plot of log-transformed interquantile range (IQR; 90th–10th) at each CpG, values generated independently in each Nicoyan and non-Nicoyan group. Blue 41,695 CpGs had higher variability in Nicoyans. Red 98,073 CpGs had higher variability in non-Nicoyans. Gray insignificant variability, less than 20% IQR between groups. Significance value from Wilcoxon signed-rank test of IQR values between Nicoyans and non-Nicoyans. b Number of sites with a β value IQR greater than 5% in each age group. Blue Nicoyans, gray non-Nicoyans. β values were corrected for cell-type proportions

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