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Table 1 ATR-X methylation signature: significant regions detected by methylation array in ATR-X patients (n = 17) compared with controls (n = 210)

From: Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome

Chr Region start Region stop # Probes Nearest gene Distance to gene (bp) Within CpG island Gene promoter/intragenic
chr1 228291476 228291715 5 C1orf35 453 No
chr3 107810351 107810801 6 CD47 415 Yes
chr3 109056339 109056907 4 DPPA4 0 No Promoter
chr4 124222 125122 5 ZNF718 0 Yes Intragenic/promoter
chr5 23506728 23507762 13 PRDM9 0 No promoter
chr5 134073420 134073589 5 CAMLG 581 No
chr5 150284292 150284806 9 ZNF300 0 Yes Promoter
chr5 150325572 150326872 13 ZNF300P1 0 Yes Promoter
chr6 168045258 168045898 5 LOC401286 21624 No
chr6 34498908 34499514 5 PACSIN1 0 Yes Intragenic
chr8 43131250 43132517 9 POTEA 15068 Yes
chr10 38069509 38069955 4 ZNF248 0 Yes Intragenic
chr16 10479552 10480299 6 ATF7IP2 0 Yes Promoter
chr19 12305543 12306507 7 LOC100289333 0 Yes Promoter
chr20 623079 623431 4 SRXN1 3837 Yes
chrY 21664286 21665031 4 BCORP1 0 Yes Promoter
  1. Significant regions: Human reference genome Hg19. Probes >4, estimate (net methylation difference) > ± 20%, F value >50, p value <0.01. Gene promoters were defined as any sequence immediately surrounding the annotated 5ʹ end of the gene