Fig. 4
From: Assessing histone demethylase inhibitors in cells: lessons learned
Effect of various KDM inhibitors described in the literature on KDM5B-mediated H3K4me3 methylation in HeLa cells. a Effect of Pan-KDM inhibitors IOX1 [30] and JIB-04 E as well as inactive control compound JIB-04 Z [16] on KDM5B-mediated H3K4me3 demethylation, b effect of KDM6A/B inhibitor GSK-J4 and inactive control compound GSK-J5 [21, 31] on KDM5B-mediated H3K4me3 demethylation. Data represent the average and SEM of at least 100 cells