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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis

Fig. 5

Liver and pancreas histological analyses. a Left: representative pictures from hematoxylin and eosin staining of liver sections around the lobular areas in wild-type and macroH2A1.2 Tg mice fed with a HF diet. Right: NAFLD and inflammation were scored using a semiquantitative system that grouped histological features into broad categories (steatosis, hepatocellular injury, portal inflammation, fibrosis and miscellaneous features) [48]. b Left representative pictures from hematoxylin and eosin staining of pancreatic sections in wild-type and macroH2A1.2 Tg mice fed with a HF diet. Right an evaluation of interlobular and intralobular fat % in pancreas sections was performed, and combined into a Mathur score [49]

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