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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing

Fig. 7

Top panel shows ChIP-seq tracks for PRC1 (H2Aub1, Ring1b), PRC2 (H3K27me3, Suz12, Ezh2), Wapal, CTCF, and BirA only as a negative control. Scale for each track is listed. Primers for 3C are shown below the gene, with the anchor primer labeled. Bottom panel normalized interaction frequency for different primers from cells infected with the empty vector or two different shRNAs to Wapal. Asterisk indicates a statistically significant (p value <0.05) reduction from empty vector

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