Table 3 Features of validated differentially methylated positions (DMPs)
DMP | Genomic location | CGI | Promoter MEFs | Promoter ESCs | Enhancer MEFs | Enhancer ESCs |
|---|---|---|---|---|---|---|
Hypo1 | Intergenic | No | H3K4m3/H3K27m3 | H3K4m3 | H3K4m1 | |
Hypo2 (Dyx1c1) | Promoter region | Yes | H3K4m3 | H3K4m3 | ||
Hypo3 | Intragenic (intron) | No | H3K4m1 | |||
Hypo4 | Intragenic (intron) | No | H3K4m1 | |||
Hypo5 | Intragenic (intron) | No | H3K4m3 | H3K4m1/H3K27ac | H3K4m1 | |
Hypo6 | Promoter region | No | H3K27m3 | H3K27m3 | H3K4m1 | H3K4m1/H3K27ac |
Hypo7 | Intragenic (intron) | Yes | H3K4m3/H3K27m3 | H3K27m3 | H3K4m1 | |
Hypo8 (HoxD9) | Promoter region | Yes | H3K4m3/H3K27m3 | H3K4m3/H3K27m3 | H3K4m1 | |
Hypo9 | Promoter region | Yes | H3K4m3/H3K27m3 | H3K4m3 | H3K4m1/H3K27ac | |
Hypo10 | Promoter region | Yes | H3K4m3/H3K27m3 | H3K4m3/H3K27m3 | H3K4m1/H3K27ac | H3K4m1 |
Hyper1 (HoxA9) | Promoter region | No | H3K4m3 | H3K4m3/H3K27m3 | ||
Hyper2 (HoxA10) | Promoter region | No | H3K4m3/H3K27m3 | H3K27m3 | H3K4m1 | |
Hyper3 | Promoter region | No | H3K4m3/H3K27m3 | H3K27m3 | H3K4m1 | |
Hyper4 (Tnfaip2) | Promoter region | Yes | H3K4m3 | H3K4m3 | H3K4m1 | H3K4m1 |
Hyper5 | Intragenic (intron) | No | ||||
Hyper6 (Pitx1) | Promoter region | Yes | H3K4m3/H3K27m3 | H3K4m3/H3K27m3 | H3K4m1 | |
Hyper7 | Intragenic (intron) | No | ||||
Hyper8 | Intergenic | Yes | H3K4m3 | H3K4m3 | H3K4m1 |