Fig. 2From: Profiling placental and fetal DNA methylation in human neural tube defectsTissue distribution of unadjusted p values from linear modeling of differential methylation in NTDs. Distribution of p values from the comparison of DNA methylation for spina bifida to control samples at each of 442,091 CpG sites (left) and for anencephaly to controls samples at each of 442,091 CpG sites (right), including fetal gestational age and sex as additive covariates. Flat distributions indicate equal likelihood of significant and non-significant tests, while left-peaking distributions indicate greater likelihood of significant testsBack to article page