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Table 1 Top 30 most hypomethylated CpG sites in naïve CD4+ T cells from healthy African-Americans compared to European Americans

From: Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity

CpG site Associated gene African-American average β European-American average β Δβ P value Location (chromosome: HG19 position)
cg26069044 NRGN 0.32 0.73 −0.41 1.82E−05 11:124613956
cg19651115   0.33 0.71 −0.37 1.20E−10 12:11700343
cg18232235   0.54 0.88 −0.34 3.61E−07 12:11700321
cg15131258 C20orf71 0.38 0.69 −0.31 5.45E−10 20:31805182
cg11738485 HOOK2 0.15 0.45 −0.31 8.55E−03 19:12877000
cg22068400   0.22 0.52 −0.31 9.56E−07 2:90016264
cg04193820 RNF135 0.17 0.46 −0.30 5.48E−12 17:29297414
cg08896939 RNF135 0.20 0.49 −0.29 2.15E−10 17:29297380
cg27436995 FBXL16 0.36 0.64 −0.29 1.54E−03 16:743998
cg17920646   0.39 0.67 −0.29 8.67E−04 8:216578
cg18136963   0.13 0.41 −0.28 1.54E−03 6:139013146
cg10578777   0.57 0.84 −0.27 2.07E−04 12:7781093
cg27415324   0.59 0.85 −0.27 1.38E−07 22:17901078
cg06864789   0.19 0.45 −0.26 9.11E−04 6:139012992
cg24506221 GSTM1 0.07 0.32 −0.26 2.94E−03 1:110230401
cg06417478 HOOK2 0.16 0.41 −0.25 3.19E−03 19:12876846
cg04554929   0.10 0.35 −0.25 3.27E−05 8:105342491
cg06202470   0.68 0.93 −0.24 2.13E−07 12:11700489
cg25828445   0.57 0.81 −0.24 3.08E−04 12:7781288
cg00817464 XPNPEP1 0.42 0.65 −0.24 4.65E−03 10:111662876
cg05886698 DDX53 0.67 0.90 −0.24 1.44E−06 X:23018110
cg24536782   0.36 0.60 −0.24 3.65E−03 8:216659
cg00239353 IL32 0.51 0.74 −0.23 1.52E−08 16:3115133
cg04752818 INTS1 0.63 0.87 −0.23 3.35E−06 7:1536622
cg08477332 S100A14 0.22 0.45 −0.23 1.47E−03 1:153590243
cg02025737   0.61 0.84 −0.23 2.46E−03 15:33384751
cg10044179 C21orf81 0.28 0.50 −0.22 2.43E−05 21:15352983
cg15641364 TAGLN2 0.17 0.40 −0.22 2.71E−07 1:159892206
cg01280390 CSGALNACT1 0.27 0.49 −0.22 4.86E−05 8:19363452
cg16154810 CERK 0.24 0.46 −0.22 6.06E−03 22:47135258