Fig. 5

Core chromosomes are enriched with euchromatin while accessory chromosomes are enriched with heterochromatin. Core chromosomes (Chr) 1 (6.09 Mb) and 13 (1.19 Mb) are strongly enriched for H3K4me2 (green) and accessory Chr 14 (0.77 Mb) and 21 (0.41 Mb) are enriched for H3K9me3 (red) and H3K27me3 (orange), marks for obligate and facultative heterochromatin, respectively. There is no strong correlation between location of centromeres and enrichment for any of the histone modifications tested. H3K9me3 correlates with regions enriched for TE and H3K27me3 is found mostly in subtelomeric regions on core chromosomes. H3K27me3 is, however, found throughout most of the accessory chromosomes. For each histone modification regions with statistically significant enrichment (see “Methods” for details) are depicted by rectangles in the same color. The ruler indicates chromosome coordinates (Coor, in Mb), and GC-content (%GC, red), centromere position determined by GFP–CenH3 enrichment (Cen, black), location of coding sequences (CDS, blue) and active or inactive transposable elements (TE, marine) are shown