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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects

Fig. 5

Distinct alterations in homeobox gene transcription arising during and after the window of EtOH exposure. Neural stem cells were cultured in the presence of 160 or 240 mg/dL EtOH for 3 days, followed by a 4-day recovery in media lacking EtOH. Cells were harvested at days-3 and 7, and transcript levels measured using RT-qPCR. Graphs represent three independent replicates (N = 3), with two independent RT reactions and three qPCR measurements for each RT. Differences were measured using a one-way ANOVA, error bars represent SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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Epigenetics & Chromatin

ISSN: 1756-8935