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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: BIDCHIPS: bias decomposition and removal from ChIP-seq data clarifies true binding signal and its functional correlates

Fig. 4

Correlation analysis with motif counts in peaks and peak-ranking analysis. a Pearson’s correlation coefficients between different model scores in peaks and DNA-binding motif counts computed for all 17 TFs from the K562 cell line. b, c Scatter plots of the PCC values for estimate B with the PCC values for the other two estimates. d Grid plot identifying the binding estimate that correlates best with motif frequencies for a given cell line and transcription factor. e Curves showing the fractions of peaks within a moving window of 1000 peaks that contain at least a single motif, when ranked using different criteria. f Venn diagrams showing the degrees of overlap between corresponding sextiles of peaks ranked by different criteria

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