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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Strategies for precision modulation of gene expression by epigenome editing: an overview

Fig. 1

(Epi)Genome editing systems. a Zinc Finger Nuclease (ZFN), b Transcription-Activator-Like Effector Nuclease (TALEN), c CRISPR/Cas9, d Zinc Finger (ZF) with a DNA methyltransferase effector domain, e Transcription-Activator-Like Effector (TALE) with a histone methyltransferase, and f Catalytically deactivated Cas9 (dCas9) and sgRNA from with a histone acetyltransferase. Components are not to scale as critical features are exaggerated and some non-variable features are removed

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