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Figure 5 | Epigenetics & Chromatin

Figure 5

From: Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

Figure 5

DNA Methylation pattern of L1Md_Tf (L1), major satellites (mSat), and IAPLTR1 (IAP) in primordial germ cells (PGCs). (A) DNA methylation patterns (for explanation see Figure  1). (B) Absolute DNA methylation levels and percentage of hemimethylated CpG dyads in relation to all methylated CpG dyads. PGCs were sorted and analyzed at 24-hour intervals from 9.5 until 13.5 days post-coitum (dpc). DNA methylation decreased continuously, with a stable relative level of hemimethylated CpG positions.

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Epigenetics & Chromatin

ISSN: 1756-8935