CG Methylation in keratinocytes and fibroblasts. (a-b) Methylation status of all CGs in (a) keratinocytes (Ker) at 36X coverage and in (b) fibroblasts (Fb) at 91X coverage. (c) Average methylation of CGs in different genomic locations. Each CG is grouped one of the six genomic locations (Upstream, Promoter, 5’ UTR, Exon, Intron, or 3’ UTR) according to the transcription start site (TSS) and coding sequence (CDS). (d-f) Comparison of average CGI methylation for Fb versus Ker in different CGI groups: (d) CGIs in Promoter, (e) CGIs in Exons, and (f) the other CGIs.