Table 4 List of top 20 hypomethylated CpG sites in the genebody of genes from high maternal folic acid diet
Chromosome | Start | End | Gene | Total CpG LMFA | Total CpG HMFA | Methylation difference | P value |
|---|---|---|---|---|---|---|---|
Male | Â | Â | Â | Â | Â | Â | Â |
Chr1 | 182625573 | 182625574 | Mixl1 | 28 | 10 | -0.76 | 0.00 |
Chr2 | 25376181 | 25376182 | Traf2 | 24 | 14 | -0.77 | 0.00 |
Chr3 | 37380649 | 37380650 | Spata5 | 14 | 18 | -0.78 | 0.00 |
Chr5 | 145038432 | 145038433 | Baiap2l1 | 58 | 20 | -0.87 | 0.00 |
Chr5 | 145038431 | 145038432 | Baiap2l1 | 28 | 20 | -0.73 | 0.00 |
Chr6 | 63336567 | 63336568 | Grid2 | 12 | 11 | -0.83 | 0.00 |
Chr8 | 119917212 | 119917213 | Cmip | 12 | 10 | -0.80 | 0.00 |
Chr9 | 49203682 | 49203683 | Drd2 | 14 | 7 | -0.93 | 0.00 |
Chr10 | 86298137 | 86298138 | Nt5dc3 | 20 | 6 | -0.83 | 0.00 |
Chr11 | 89264853 | 89264854 | 4932411E22Rik | 12 | 8 | -1.00 | 0.00 |
Chr11 | 88387073 | 88387074 | Msi2 | 11 | 10 | -0.90 | 0.00 |
Chr12 | 73229241 | 73229242 | Ccdc175 | 19 | 6 | -0.83 | 0.00 |
Chr13 | 117804995 | 117804996 | Parp8 | 12 | 6 | -1.00 | 0.00 |
Chr16 | 49910445 | 49910446 | Cd47 | 8 | 10 | -1.00 | 0.00 |
Chr16 | 96296259 | 96296260 | Brwd1 | 24 | 8 | -0.83 | 0.00 |
Chr17 | 80761785 | 80761786 | Arhgef33 | 20 | 13 | -0.77 | 0.00 |
Chr17 | 64485735 | 64485736 | Fert2 | 9 | 14 | -0.82 | 0.00 |
Chr18 | 36751828 | 36751829 | Ankhd1 | 20 | 10 | -0.90 | 0.00 |
Chr19 | 5690281 | 5690282 | Map3k11 | 20 | 13 | -0.80 | 0.00 |
ChrX | 98171409 | 98171410 | Tex11 | 10 | 6 | -1.00 | 0.00 |
Female | Â | Â | Â | Â | Â | Â | Â |
Chr1a | 106890569 | 106890570 | Cdh20 | 15 | 14 | -0.73 | 0.00 |
Chr3 | 53010469 | 53010470 | Lhfp | 12 | 10 | -0.92 | 0.00 |
Chr4 | 137849617 | 137849618 | Kif17 | 9 | 14 | -0.86 | 0.00 |
Chr4 | 142704605 | 142704606 | Prdm2 | 15 | 11 | -0.73 | 0.00 |
Chr4 | 21913536 | 21913537 | 6230409E13Rik | 23 | 10 | -0.71 | 0.00 |
Chr4 | 46546442 | 46546443 | Trim14 | 16 | 11 | -0.75 | 0.00 |
Chr4 | 117003265 | 117003266 | Rnf220 | 16 | 6 | -0.83 | 0.00 |
Chr5 | 148775977 | 148775978 | Mtus2 | 20 | 14 | -0.76 | 0.00 |
Chr5 | 37274842 | 37274843 | Ppp2r2c | 14 | 17 | -0.75 | 0.00 |
Chr8 | 121359642 | 121359643 | Cdh13 | 17 | 10 | -0.74 | 0.00 |
Chr9 | 21909321 | 21909322 | Cnn1 | 10 | 6 | -1.00 | 0.00 |
Chr9 | 44605440 | 44605441 | Tmem25 | 16 | 10 | -0.75 | 0.00 |
Chr11 | 96309521 | 96309522 | Gm11529 | 25 | 10 | -0.88 | 0.00 |
Chr11 | 118204319 | 118204320 | Timp2 | 20 | 7 | -0.81 | 0.00 |
Chr11 | 98634354 | 98634355 | Nr1d1 | 7 | 15 | -0.87 | 0.00 |
Chr15 | 99627500 | 99627501 | Lima1 | 25 | 22 | -0.74 | 0.00 |
Chr15 | 59208541 | 59208542 | Nsmce2 | 9 | 6 | -1.00 | 0.00 |
Chr16 | 49910445 | 49910446 | Cd47 | 10 | 12 | -0.83 | 0.00 |
Chr17 | 26016873 | 26016874 | Wfikkn1 | 36 | 20 | -0.73 | 0.00 |
Chr17 | 28437426 | 28437427 | Ppard | 8 | 22 | -0.83 | 0.00 |