Table 2 List of hypomethylated CpG sites in the promoter of genes from high maternal folic acid diet
Chromosome | Start | End | Gene | Total CpG LMFA | Total CpG HMFA | Methylation difference | P value |
|---|---|---|---|---|---|---|---|
Male-CpG | Â | Â | Â | Â | Â | Â | Â |
Chr2 | 104335383 | 104335384 | Hipk3 | 6 | 10 | -0.80 | 0.01 |
Chr2 | 118590048 | 118590049 | A430105I19Rik | 6 | 7 | -0.83 | 0.00 |
Chr2 | 164156736 | 164156737 | Svs5 | 5 | 6 | -0.83 | 0.02 |
Chr2 | 171789984 | 171789985 | 1700028P15Rik | 17 | 5 | -0.80 | 0.00 |
Chr4 | 135283630 | 135283631 | Il22ra1 | 5 | 5 | -0.80 | 0.05 |
Chr5 | 122070856 | 122070857 | Acad12 | 6 | 11 | -0.73 | 0.01 |
Chr7 | 3219409 | 3219410 | Mir291b | 8 | 11 | -0.75 | 0.00 |
Chr7 | 7253725 | 7253726 | Clcn4-2 | 6 | 9 | -0.72 | 0.01 |
Chr7a | 15208940 | 15208941 | Gm18756 | 10 | 12 | -0.83 | 0.00 |
Chr7 | 91836603 | 91836604 | 2610206C17Rik | 6 | 5 | -0.83 | 0.02 |
Chr8 | 34495178 | 34495179 | Purg | 5 | 5 | -0.80 | 0.05 |
Chr8 | 73034757 | 73034758 | Uba52 | 6 | 6 | -0.83 | 0.02 |
Chr8 | 77516944 | 77516945 | Hmgxb4 | 6 | 15 | -0.77 | 0.00 |
Chr9 | 66892554 | 66892555 | Tpm1 | 15 | 6 | -0.73 | 0.00 |
Chr10 | 53239171 | 53239172 | Gm20597 | 8 | 7 | -0.75 | 0.01 |
Chr12 | 3235150 | 3235151 | 1700012B15Rik | 16 | 18 | -0.88 | 0.00 |
Chr13 | 53382125 | 53382126 | Ror2 | 6 | 5 | -0.80 | 0.02 |
Chr13 | 53382128 | 53382129 | Ror2 | 6 | 5 | -1.00 | 0.00 |
Chr13 | 97839933 | 97839934 | Fam169a | 5 | 8 | -0.75 | 0.02 |
Chr13 | 100671338 | 100671339 | Cartpt | 5 | 5 | -0.80 | 0.05 |
Chr14 | 67628989 | 67628990 | Bnip3l | 7 | 8 | -0.75 | 0.01 |
Chr19 | 5690281 | 5690282 | Pcnxl3 | 20 | 13 | -0.80 | 0.00 |
Female-CpG | Â | Â | Â | Â | Â | Â | Â |
Chr2 | 127618583 | 127618584 | 1500011K16Rik | 11 | 20 | -0.85 | 0.00 |
Chr5a | 100468191 | 100468192 | Enoph1 | 11 | 5 | -0.71 | 0.01 |
Chr6a | 52196197 | 52196198 | Hoxa11 | 5 | 5 | -0.80 | 0.05 |
Chr6 | 100476908 | 100476909 | 1700049E22Rik | 10 | 5 | -0.80 | 0.00 |
Chr7 | 26326796 | 26326797 | Ceacam2 | 6 | 15 | -0.77 | 0.00 |
Chr7 | 29528469 | 29528470 | Mrps12 | 16 | 5 | -0.80 | 0.00 |
Chr7 | 86988105 | 86988106 | Anpep | 12 | 5 | -0.83 | 0.00 |
Chr8 | 87469964 | 87469965 | Rtbdn | 7 | 6 | -0.86 | 0.00 |
Chr8 | 116657191 | 116657192 | Nudt7 | 14 | 5 | -0.71 | 0.01 |
Chr9 | 109833746 | 109833747 | Mtap4 | 8 | 14 | -0.71 | 0.00 |
Chr10 | 76992742 | 76992743 | Itgb2 | 8 | 7 | -0.71 | 0.01 |
Chr10 | 80846466 | 80846467 | Dohh | 8 | 13 | -0.69 | 0.00 |
Chr11 | 88727116 | 88727117 | Akap1 | 6 | 5 | -0.80 | 0.02 |
Chr11 | 115184397 | 115184398 | Ush1g | 12 | 5 | -0.75 | 0.01 |
Chr11 | 118204319 | 118204320 | BC100451 | 20 | 7 | -0.81 | 0.00 |
Chr11 | 119909421 | 119909422 | Aatk | 7 | 5 | -0.71 | 0.03 |
Chr11 | 120051942 | 120051943 | 2810410L24Rik | 10 | 5 | -0.70 | 0.02 |
Chr12 | 52447904 | 52447905 | G2e3 | 8 | 5 | -0.75 | 0.02 |
Chr14a | 63380523 | 63380524 | Ints6 | 5 | 6 | -0.80 | 0.02 |
Chr15 | 81561248 | 81561249 | Rangap1 | 13 | 5 | -0.72 | 0.01 |
Chr17 | 52020946 | 52020947 | Gm20098 | 9 | 7 | -0.71 | 0.00 |
Chr18 | 38762241 | 38762242 | Spry4 | 6 | 5 | -0.83 | 0.02 |
Chr18 | 60933042 | 60933043 | Rps14 | 9 | 8 | -0.76 | 0.00 |
Chr19 | 7070128 | 7070129 | Trpt1 | 8 | 6 | -0.71 | 0.03 |