Figure 2

Relative expression of the genes that exhibited hypermethylation (a, b) and hypomethylation (c, d). The results were normalized to Hprt transcript expression and were expressed as relative values in comparison with corresponding transcripts from low maternal folic acid (LMFA). Results represent mean ± standard deviation (SD); asterisks denote statistically significant change (*P < 0.05, **P < 0.01, ***P < 0.001).