Figure 2

Induced loss of G9a in Mili^-/-mice results in severe spermatogenic defects. (A) Hematoxylin and eosin stained adult testis sections from the indicated genotypes. The inset highlights the basal portion of the tubule containing spermatogonia and meiotic cells or spermatagonia only in the case of G9a^CKO; Mili^KO mice. (B) Representative image of G9a^CKO; Mili^KO hematoxylin and eosin stained adult testis section, the black square indicates Sertoli-only tubules. The percentage of Sertoli cell-only tubules in the respective genotypes is shown. The results are derived from four mice of the indicated genotypes and the s.e.m is shown.