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Table 5 Regression analysis accounting for individual variation indicates little effect of between-individual variability of DNA methylation on transcriptional noise

From: DNA methylation and transcriptional noise

Predictors

Sum of square

Degrees of freedom (df)

F value

P value

VIFa

Intercept

214.6

1

578.390

<10-4

1.03

Expression

28,164.2

1

75,900.35

<10-4

1.30

Gene length

7.6

1

20.352

<10-4

2.00

Gene body methylation

17.3

1

46.541

<10-4

1.04

Promoter methylation

43.2

1

116.420

<10-4

3.89

Individual

0.3

2

0.430

0.651

4.05

Individual:gene body methylation

0.3

2

0.455

0.634

 

Adjusted R2

   

0.87

 
  1. aVariation inflation factor (VIF) approximated as (generalized VIF)1/(2*df)[59].