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Figure 2 | Epigenetics & Chromatin

Figure 2

From: Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

Figure 2

Comparison of the genomic distribution of Illumina-annotated CpG probe classes within each HIL-annotated CpG probe class. Within HCs, ICshores and LCs, the majority of probes were categorized into the respective Illumina-annotated CpG class. However, even though ICs and ICshores have the same CpG density, the distribution of probes based on Illumina CpG classes was different between these two HIL classes, suggesting a functional difference between ICs that border HCs and isolated ICs. HC, high-density CpG island; HIL, high-density CpG island (HC), intermediate-density CpG island (IC) and non-island (LC); ICshore, intermediate-density CpG island shore.

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