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Table 1 Sub-fertility of CTCFL mutant mice

From: The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

Genotype

Ctcfl del/+

Ctcfl del/del

Number (percentage) of breedings w/o offspring

3/60 (5%)

14/27 (51.9%)

Average number of offspring per litter (± SD)

7.7 ± 2.6

6.4 ± 2.8

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Epigenetics & Chromatin

ISSN: 1756-8935