Figure 1
From: A unified phylogeny-based nomenclature for histone variants
Unrooted H2A phylogeny. H2A.Z is a monophyletic clade present in all eukaryotes, while macroH2A (mH2A) is restricted to animals and H2A.B (H2A.Bbd) and H2A.L (H2AL) are confined to mammals. Paraphyletic or polyphyetic H2A.X and replication-coupled H2As have diverged repeatedly. Alignments and trees constructed using default ClustalW parameters and displayed using Dendroscope [45].