Figure 2
From: MK3 controls Polycomb target gene expression via negative feedback on ERK
PRC1/chromatin dissociation, not loss of H3K27me3, correlates with transcription. (A,B) Chromatin immuno-precipitation (ChIP) analysis of PRC1 protein binding, histone H3K27me3 (A) and H3S28ph marking (B) at known PRC1 target and non-target loci in G1-arrested (starved) and mitogen-stimulated TIG3 cells. ChIP antisera are indicated in the figures (ChIP antibodies (aB)). (Statistical significance: *P < 0.05, **P < 0.01; t-test.