Figure 1
From: Generation of bivalent chromatin domains during cell fate decisions
Chromatin marks at the telomeric region of chromosome 16p in embryonic stem (ES) cells. (a) The genes, multispecies conserved regulatory sequences (MCS-R1-4) and CpG islands (CGI) are shown at the top. The red shaded box represents the α globin cluster. The y axis represents the enrichment of chromatin immunoprecipitation (ChIP) DNA over input DNA. (b) ChIP quantitative PCR (qPCR) data at selected amplicons. Ery = primary human erythroblasts; Ery10% = mixed population consisting of 10% erythroblasts and 90% Ly; ES = human ES cells; Ly = Epstein-Barr virus (EBV)-transformed lymphoblastoid cell line. The fold enrichment has been calculated relative to a control sequence in the ACTB promoter. The error bars show the standard deviation of three independent experiments. **P < 0.05; ***P < 0.01 (both by Student's t test).