Chromatin marks at the telomeric region of chromosome 16p in embryonic stem (ES) cells. (a) The genes, multispecies conserved regulatory sequences (MCS-R1-4) and CpG islands (CGI) are shown at the top. The red shaded box represents the α globin cluster. The y axis represents the enrichment of chromatin immunoprecipitation (ChIP) DNA over input DNA. (b) ChIP quantitative PCR (qPCR) data at selected amplicons. Ery = primary human erythroblasts; Ery10% = mixed population consisting of 10% erythroblasts and 90% Ly; ES = human ES cells; Ly = Epstein-Barr virus (EBV)-transformed lymphoblastoid cell line. The fold enrichment has been calculated relative to a control sequence in the ACTB promoter. The error bars show the standard deviation of three independent experiments. **P < 0.05; ***P < 0.01 (both by Student's t test).