Figure 4

Endo-cleavage profiles at the 5′ ends of genes for the activated oocyte chromatin. (a) The number of tags was plotted as a function of distance to the dyad of the 'plus-one’ nucleosome, defined by peak H3K4me2/3 nucleosomes near transcription start sites for the 3903 'H3K4me2/3-anchored’ genes [20]. Tags that mapped to sense-strand and anti-sense-strand were plotted separately. A set of nucleosome cores are indicated by ovals (scaled to indicate a size of 147 nt). To contrast short and longer-scale periodicities, several expanded views are plotted in panel (b). (c) A schematic diagram showing the analysis.