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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes

Fig. 5

MMP-2 is selectively targeted to transcription start sites of active genes a Heatmaps and average peak profiles of the RPKM intensity (y-axis) of ProMMP2-3xHA, RNA PolII, DNA accessible regions (ATAC), H3K4me3 and H3K18ac centered at TSSs over a ± 2 kb window (x-axis). All protein coding genes were evenly separated into 4 groups based on the average transcripts per million, as indicated (high, medium, low or no expression). b Expanded average peak profiles of ProMMP2-3xHA (top) and RNA PolII (bottom), from a, plotting RPKM intensity (y-axis) centered at TSSs over a ± 2 kb window (x-axis)

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Epigenetics & Chromatin

ISSN: 1756-8935